Chlormadinone acetate (CMA) minangka agonis reseptor progesteron (PR) sing kuat, antagonis reseptor androgen (AR) parsial lan antagonis reseptor glukokortikoid (GR) sing lemah.Chlormadinone ikatan karo PRs, sing nyebabake ekspresi gen responsif progesteron.
Jeneng produk | Klormadinone asetat |
Jeneng Kimia | 17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione |
Jeneng Liyane | Clormadinoneacetate;chloromadinone17-acetate;6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione;17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione,6-Chloro- 6-dehydro-17α-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate; 17-alpha-acetoxy-;ChChemicalbooklormadinoneacetate,17α6-Acetate -chloro-4,6-pregnadiene-3,20-dione,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate,6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin ,Matrol,Mens;(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12 ,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetate |
Nomer CAS | 302-22-7 |
Formula Molekul | C23H29ClO4 |
Formula Bobot | 404.93 |
Penampilan | Bubuk kristal putih nganti kuning;Ora ambune, Ora ana rasa |
Assay | 98,0% min |
Titik Lebur | 212°C |
Titik didih | 512,5±50,0 °C |
Puncak Penyerapan | 1,1345 g/cm3 |
Paket | 20kg/bag/drum, 25kg/bag/drum, utawa sing dibutuhake |
Lumbung | Simpen wadhah sing ditutup kanthi rapet ing papan sing garing lan adhem.Aja kena sinar srengenge langsung. |
COA & MSDS | kasedhiya |
Aplikasi | Kanggo tujuan riset |
UJI | KRITERIA PENAMPILAN | Asil |
Identifikasi | TLC | Positif |
spektrum UV | Positif | |
spektrum IR | Positif | |
Karakteristik | Bubuk kristal putih utawa kuning | manut |
Titik lebur | 211 ~ 215 ℃ | 211~214 ℃ |
Rotasi optik spesifik | ﹣10° ~﹣14° | ﹣12,5° |
Kelarutan | bebas larut ing kloroform, larut ing asetonitril, rada larut ing etanol lan eter lan praktis ora larut ing banyu. | manut |
Rugi ing pangatusan | ≤0,5% | 0,21% |
Sisa ing ignition | ≤0,1% | 0,04% |
steroid liyane | ≤1,0% | 0,59% |
Logam abot | ≤20ppm | Lulus |
Arsenik | ≤2ppm | Lulus |
Assay | ≥98,0% | 98,9% |
Sisa pelarut (GC) | Aseton ≤5000ppm Metanol≤3000ppm Piridin≤200ppm | Lulus Lulus Lulus |
Chlormadinone acetate minangka obat progestin lan antiandrogen sing digunakake ing pil kontrol lair kanggo nyegah meteng, minangka komponen terapi hormon menopause, ing perawatan kelainan ginekologi, lan ing perawatan kondisi gumantung androgen kaya prostat nggedhekake lan kanker prostat. lanang lan kukul lan hirsutism ing wanita.
Kepiye carane njupuk Chlormadinone acetate?
Kontak:erica@zhuoerchem.com
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Wektu timbal
≤100kg: ing telung dina kerja sawise pembayaran ditampa.
>100kg: seminggu
Sampel
kasedhiya.
Paket
20kg/bag/drum, 25kg/bag/drum
utawa kaya sing dibutuhake.
Lumbung
Simpen wadhah sing ditutup kanthi rapet ing papan sing garing lan adhem.
Aja kena sinar srengenge langsung.